1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride
CAS: 63659-19-8
Molecular Formula: C18H30ClNO3
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride - Names and Identifiers
| Name | 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride |
| Synonyms | SL 75212 BETAXOLOL HCL BETAXOLOL CHLOROHYDRATE Betaxolol Hydrochloride BETAXOLOL HYDROCHLORIDE BETAXOLOL HYDROCHLORIDE MONOHYDRATE (+-)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propano 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-olhydroc 1-[4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOXY]-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride |
| CAS | 63659-19-8 |
| EINECS | 264-384-3 |
| InChI | InChI=1/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H |
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride - Physico-chemical Properties
| Molecular Formula | C18H30ClNO3 |
| Molar Mass | 343.89 |
| Melting Point | 116° |
| Boling Point | 448°C at 760 mmHg |
| Flash Point | 224.7°C |
| Solubility | H2O: 36mg/mL, soluble |
| Vapor Presure | 8.26E-09mmHg at 25°C |
| Appearance | solid |
| Color | white |
| Merck | 14,1182 |
| Storage Condition | 2-8°C |
| In vitro study | Betaxolol protects retinal neurons. Betaxolol attenuates NMDA induction when β-adrenoceptor agonists are ineffective. Glutamate-induced LDH release was essentially completely blocked by the addition of Betaxolol (10 μm). Betaxolol (100 μm) is effective in preventing the release of LDH in cortical tissue caused by hypoxia. |
| In vivo study | Changes in calreticulin and ChAT immunoreactivity were reduced and the B- wave was prevented by intraperitoneal injection of Betaxolol before regional anemia and reperfusion injury in rats. The inclusion of Betaxolol can partially block the changes caused by NMDA and hypoxia/glucose. |
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| RTECS | UA9823000 |
| HS Code | 2922504500 |
| Toxicity | LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury) |
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride - Reference Information
| Update Date: | 2022/11/12 10:05:38 |
| biological activity | Betaxolol (SL 75212) is a beta 1 adrenergic receptor blocker with an IC50 of 6 m. |
| Target | Value |
| β1-adrenergic receptor | 6 μM |
Last Update：2024-04-09 19:05:13
![1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride](http://res.chembk.com/assets/str/2d/6/63/63659-19-8.png)
Supplier List
Multiple SpecificationsSpot supply
Product Name: SL75212 Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Betaxolol hydrochloride? Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Betaxolol hydrochloride Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride Request for quotation
CAS: 63659-19-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 63659-19-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple SpecificationsSpot supply
Product Name: SL75212 Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Betaxolol hydrochloride? Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Betaxolol hydrochloride Visit Supplier Webpage Request for quotationCAS: 63659-19-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride Request for quotation
CAS: 63659-19-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 63659-19-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History
1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride
SODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATE
SODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATESODIUM 1-OCTANESULFONATE, MONOHYDRATE